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Clinical Trial
. 2005 Apr;26(2):211-22.
doi: 10.1016/j.cct.2005.01.001.

Design and baseline characteristics of participants in the study of antihypertensive therapy in children and adolescents with autosomal dominant polycystic kidney disease (ADPKD)

Melissa A Cadnapaphornchai  1 , Godela M Fick-Brosnahan, Irene Duley, Ann M Johnson, John D Strain, Curt G DeGroff, Robert W Schrier
Affiliations
Clinical Trial

Design and baseline characteristics of participants in the study of antihypertensive therapy in children and adolescents with autosomal dominant polycystic kidney disease (ADPKD)

Melissa A Cadnapaphornchai et al. Contemp Clin Trials. 2005 Apr.

Abstract

In this manuscript, we describe our ongoing randomized clinical trial to assess the efficacy of blood pressure control with angiotensin converting enzyme (ACE) inhibition on renal cyst growth over a 5-year study period in children and young adults aged 4-21 years with autosomal dominant polycystic kidney disease (ADPKD). Baseline demographic and laboratory data for the study groups are reported. Results of this study could significantly impact the standard of care for management of ADPKD in this population.

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