Association between tonsillectomy, adenoidectomy, and appendicitis
- PMID: 15839812
- DOI: 10.4321/s1130-01082005000300006
Association between tonsillectomy, adenoidectomy, and appendicitis
Abstract
Introduction: Tonsillectomy, with or without adenoidectomy, is one of the most frequent surgical procedures generally performed, especially in young patients. Several studies suggest that there is a relationship between tonsillectomy and altered MALT immune system.
Objective: To examine the possible association between tonsillectomy or adenoidectomy and the risk of subsequent appendicitis.
Material and method: A cross-sectional study was performed in 650 patients admitted to the emergency department of a general hospital in Valencia, Spain. Previous history of tonsillectomy and/or adenoidectomy was related to a history of appendectomy. A descriptive study and an analysis of the relationship between previous operations and appendicitis was performed. A multivariable analysis controlled for age and sex was also performed, including the possible interaction of the gender variable. The independent effect of each of the procedures (tonsillectomy, adenoidectomy) was tested.
Results: The 25.5% of patients had undergone tonsillectomy and 11.5% adenoidectomy; 17.5% had had an appendectomy. On average, women were operated on more frequently than men. In the bivariate analysis, both tonsillectomy and adenoidectomy were significantly associated with subsequent appendectomy. In the multivariate analysis, this association was only maintained for tonsillectomy (OR: 3.23; 95% CI: 2.11-4.94). A stratified analysis controlling for sex showed a modification of this effect, with a higher association in women (OR: 5.20; 95% CI: 2.91-9.28) than in men (OR: 1.74; 95% CI: 0.90-3.39).
Conclusions: A clear association has been found, especially in women, between previous tonsillectomy and subsequent acute appendicitis. Due to a lack of data on acute appendicitis there should be further studies to explain the findings of this study, as this could be the first described risk factor of acute appendicitis.
Similar articles
-
Childhood appendectomy, tonsillectomy, and risk for premature acute myocardial infarction--a nationwide population-based cohort study.Eur Heart J. 2011 Sep;32(18):2290-6. doi: 10.1093/eurheartj/ehr137. Epub 2011 Jun 1. Eur Heart J. 2011. PMID: 21632600
-
[Adenoidectomy, tonsillectomy and appendicitis in students of a secondary school in Toulon].Concours Med. 1962 Aug 18-25;84:4529-34. Concours Med. 1962. PMID: 13920845 French. No abstract available.
-
[Epidemiology of tonsillectomy and/or adenoidectomy in Italy].Pediatr Med Chir. 2004 May-Jun;26(3):179-86. Pediatr Med Chir. 2004. PMID: 16366401 Italian.
-
Peritonsillar abscess: clinical aspects of microbiology, risk factors, and the association with parapharyngeal abscess.Dan Med J. 2017 Mar;64(3):B5333. Dan Med J. 2017. PMID: 28260599 Review.
-
[Adenotonsillectomy in children: not yet scientifically validated].Ned Tijdschr Geneeskd. 2002 Jan 5;146(1):8-12. Ned Tijdschr Geneeskd. 2002. PMID: 11802340 Review. Dutch.
Cited by
-
Increased risk of appendectomy due to appendicitis after tonsillectomy in women: A longitudinal follow-up study using a national sample cohort.Medicine (Baltimore). 2019 May;98(19):e15579. doi: 10.1097/MD.0000000000015579. Medicine (Baltimore). 2019. PMID: 31083236 Free PMC article.
-
The Associations of Tonsillectomy with Adenoidectomy with Pneumonia and Appendicitis Based on National Sample Cohort Data from the Korean National Health Insurance Service.Int Arch Otorhinolaryngol. 2021 Feb 19;25(4):e545-e550. doi: 10.1055/s-0040-1722159. eCollection 2021 Oct. Int Arch Otorhinolaryngol. 2021. PMID: 34737825 Free PMC article.
-
Seasonal variation of appendicitis in northern Saudi Arabia.Ann Saudi Med. 2008 Mar-Apr;28(2):140-1. doi: 10.5144/0256-4947.2008.140a. Ann Saudi Med. 2008. PMID: 18398277 Free PMC article. No abstract available.
MeSH terms
LinkOut - more resources
Full Text Sources
Medical