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. 2005 Apr 15;134(2):195-8.
doi: 10.1016/j.psychres.2005.01.005.

Promoter polymorphism of second tryptophan hydroxylase isoform (TPH2) in schizophrenia and suicidality

Vincenzo De Luca  1 , Daphne Voineskos, Gregory W H Wong, Takahiro Shinkai, Claudia Rothe, John Strauss, James L Kennedy
Affiliations

Promoter polymorphism of second tryptophan hydroxylase isoform (TPH2) in schizophrenia and suicidality

Vincenzo De Luca et al. Psychiatry Res. .

Abstract

Allele and haplotype frequencies of a promoter polymorphism in the gene encoding tryptophan hydroxylase (TPH2) did not differ in 83 suicidal schizophrenic patients compared with 170 non-suicidal schizophrenic patients. These findings suggest that these 5' marker haplotypes in the TPH2 gene do not influence suicidal behavior in schizophrenia.

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