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. 2005 Apr;13(4):319-23.
doi: 10.1176/appi.ajgp.13.4.319.

A pilot study of standardized treatment in geriatric bipolar disorder

Ariel G Gildengers  1 , Benoit H Mulsant, Amy E Begley, Mary McShea, Jacqueline A Stack, Mark D Miller, Andrea Fagiolini, David J Kupfer, Robert C Young, Charles F Reynolds 3rd
Affiliations

A pilot study of standardized treatment in geriatric bipolar disorder

Ariel G Gildengers et al. Am J Geriatr Psychiatry. 2005 Apr.

Abstract

Objective: The authors sought to determine the feasibility of treating elderly adults with bipolar disorder under standardized-treatment conditions.

Methods: Thirty-one patients age 60 and older with bipolar disorder were treated in standardized pathways. Mood state was checked at each study visit with the Hamilton Rating Scale for Depression-17 item (Ham-D-17) and the Young Mania Rating Scale (YMRS).

Results: Defining "well days" as both Ham-D and YMRS scores of <or=10, the mean percentage of well days was 72.5 (range: 0%-100%) over study participation.

Conclusions: Treating older adults with bipolar disorder under standardized treatment is feasible and is associated with low symptom levels. However, most older adults with bipolar disorder do not experience sustained recovery.

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