Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 1992;78(1):28-31.
doi: 10.1007/BF00936177.

Effects of reactive oxygen intermediate scavengers on the antitoxoplasmic activity of activated macrophages

A Saito  1 , I Igarashi, K Miyahara, C Venturini, F G Claveria, T Hirose, N Suzuki, K Ono
Affiliations

Effects of reactive oxygen intermediate scavengers on the antitoxoplasmic activity of activated macrophages

A Saito et al. Parasitol Res. 1992.

Abstract

Obioactin, Lonomycin A, muramyl dipeptide, and scavengers of hydrogen radicals and of singlet oxygen were used to study the participation of.OH and 1O2 in the killing of Toxoplasma in cultures of glycogen-induced peritoneal macrophages. Both the scavengers of OH (diazabicyclooctane and histidine) and those of 1O2 (mannitol and sodium benzoate) failed to inhibit the multiplication of Toxoplasma in macrophages that were incubated with either Obioactin, Lonomycin A, or MDP. The results of these experiments demonstrate the apparent lack of an inhibitory effect of.OH and 1O2 on the multiplication of Toxoplasma, whereas the scavengers alone inhibited the growth of the parasites.

PubMed Disclaimer

References

    1. Zentralbl Bakteriol Mikrobiol Hyg A. 1984 Mar;256(3):367-80 - PubMed
    1. Zentralbl Bakteriol Mikrobiol Hyg A. 1987 May;264(3-4):446-54 - PubMed
    1. J Exp Med. 1979 Oct 1;150(4):938-49 - PubMed
    1. Zentralbl Bakteriol Mikrobiol Hyg A. 1984 Mar;256(3):356-66 - PubMed
    1. Klin Wochenschr. 1982 Jul 15;60(14):720-6 - PubMed

Publication types

MeSH terms