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Review
. 2005 May;90(5):494-9.
doi: 10.1136/adc.2003.036590.

Bisphosphonate treatment of bone disease

N J Shaw  1 , N J Bishop
Affiliations
Review

Bisphosphonate treatment of bone disease

N J Shaw et al. Arch Dis Child. 2005 May.

Abstract

In 1997 a review article on bisphosphonates in this journal identified 24 published articles relating to children at that time. Since then there has been a considerable increase in their use in clinical paediatric practice and research with there being nearly a further one hundred articles published at the time of writing.

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Figures

Figure 1
Figure 1
Structure of pyrophosphate and bisphosphonate.
Figure 2
Figure 2
Cascade of events triggered by administration of a bisphosphonate.
See this image and copyright information in PMC

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