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. 2005 May 23;340(7):1393-6.
doi: 10.1016/j.carres.2005.02.027.

One-pot synthesis of per-O-acetylated thioglycosides from unprotected reducing sugars

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One-pot synthesis of per-O-acetylated thioglycosides from unprotected reducing sugars

Geetanjali Agnihotri et al. Carbohydr Res. .

Abstract

A sequential per-O-acetylation and thioglycosidation of unprotected reducing sugars using a stoichiometric quantity of acetic anhydride and alkyl- or arylthiols is reported. These reactions, which are catalyzed by BF3.OEt2, together constitute an efficient one-pot method for the synthesis of acetylated thioglycosides.

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