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Review
. 2005 May;49(5):1671-8.
doi: 10.1128/AAC.49.5.1671-1678.2005.

Changing patterns in the selection of viral mutations among patients receiving nucleoside and nucleotide drug combinations directed against human immunodeficiency virus type 1 reverse transcriptase

Mark A Wainberg  1 , Bluma G Brenner, Dan Turner
Affiliations
Review

Changing patterns in the selection of viral mutations among patients receiving nucleoside and nucleotide drug combinations directed against human immunodeficiency virus type 1 reverse transcriptase

Mark A Wainberg et al. Antimicrob Agents Chemother. 2005 May.
No abstract available

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Figures

FIG. 1.
FIG. 1.
Prevalence of K65R and L74V mutations among genotypes of more than 80,000 isolates submitted to a commercial laboratory for resistance testing. Reprinted with permission (H. Faruki, J. Sebastian, J. Scott, J. Stamp, and E. R. Lanier, unpublished data).
FIG. 2.
FIG. 2.
HIV-1 replication in viral clones after introduction of the L74V and M184V mutations. (Adapted from reference .)
FIG. 3.
FIG. 3.
Frequencies of L74V, V118I, T215Y, and D67N/T215Y in patients with viral rebound on ABC-containing highly active ART regimens. Reprinted with permission (M. Daeumer, N. Beerenwinkel, S. Sierra, J. Klein, J. Selbig, M. Oette, G. Faetkenheuer, J. Rockstroh, D. Hoffman, H. Pfeifer, and R. Kaiser, unpublished data).
See this image and copyright information in PMC

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