doi: 10.1016/j.ijbiomac.2005.02.004.
Epub 2005 Mar 19.
Complex between triple helix of collagen and double helix of DNA in aqueous solution
Affiliations
- PMID: 15862862
- DOI: 10.1016/j.ijbiomac.2005.02.004
Item in Clipboard
Complex between triple helix of collagen and double helix of DNA in aqueous solution
Int J Biol Macromol.
2005 Jun.
Abstract
We demonstrate in this paper that one example of a biologically important and molecular self-assembling complex system is a collagen-DNA ordered aggregate which spontaneously forms in aqueous solutions. Interaction between the collagen and the DNA leads to destruction of the hydration shell of the triple helix and stabilization of the double helix structure. From a molecular biology point of view this nano-scale self-assembling superstructure could increase the stability of DNA against the nucleases during collagen diseases and the growth of collagen fibrills in the presence of DNA.
Similar articles
-
Collagen-DNA complex.Biomacromolecules. 2008 Jan;9(1):21-8. doi: 10.1021/bm7008813. Epub 2007 Dec 4. Biomacromolecules. 2008. PMID: 18052128
-
DNA as a matrix of collagen fibrils.Int J Biol Macromol. 2005 Sep 28;36(5):324-6. doi: 10.1016/j.ijbiomac.2005.07.006. Int J Biol Macromol. 2005. PMID: 16111743
-
Fiber molecular model of atelocollagen-small interfering RNA (siRNA) complex.Int J Biol Macromol. 2005 Dec 30;37(5):283-6. doi: 10.1016/j.ijbiomac.2005.11.008. Epub 2006 Jan 6. Int J Biol Macromol. 2005. PMID: 16405995
-
Triple-helical peptides: an approach to collagen conformation, stability, and self-association.Biopolymers. 2008 May;89(5):345-53. doi: 10.1002/bip.20958. Biopolymers. 2008. PMID: 18275087 Review.
-
Role of side chains in collagen triple helix stabilization and partner recognition.J Pept Sci. 2009 Mar;15(3):131-40. doi: 10.1002/psc.1082. J Pept Sci. 2009. PMID: 19053070 Review.
Cited by
-
H-ACO with Consecutive Bases Pairing Constraint for Designing DNA Sequences.Interdiscip Sci. 2024 Sep;16(3):593-607. doi: 10.1007/s12539-024-00614-1. Epub 2024 Apr 29. Interdiscip Sci. 2024. PMID: 38683280
-
Mineralized DNA-collagen complex-based biomaterials for bone tissue engineering.Int J Biol Macromol. 2020 Oct 15;161:1127-1139. doi: 10.1016/j.ijbiomac.2020.06.126. Epub 2020 Jun 16. Int J Biol Macromol. 2020. PMID: 32561285 Free PMC article.
-
Multifunctional DNA-Collagen Biomaterials: Developmental Advances and Biomedical Applications.ACS Biomater Sci Eng. 2025 Mar 10;11(3):1253-1268. doi: 10.1021/acsbiomaterials.4c01475. Epub 2025 Jan 27. ACS Biomater Sci Eng. 2025. PMID: 39869382 Free PMC article. Review.
MeSH terms
Substances
LinkOut - more resources
Full Text Sources
