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Review
. 2005 Jun;66(2-3):81-97.
doi: 10.1016/j.antiviral.2005.03.002. Epub 2005 Apr 26.

Development of antiviral therapy for severe acute respiratory syndrome

Jindrich Cinatl Jr  1 , Martin Michaelis, Gerold Hoever, Wolfgang Preiser, Hans Wilhelm Doerr
Affiliations
Review

Development of antiviral therapy for severe acute respiratory syndrome

Jindrich Cinatl Jr et al. Antiviral Res. 2005 Jun.

Abstract

A new disease, the severe acute respiratory distress syndrome (SARS), caused by the SARS coronavirus (SARS-CoV), emerged at the beginning of 2003 and rapidly spread throughout the world. Although the disease had disappeared in June 2003 its re-emergence cannot be excluded. The development of vaccines against SARS-CoV may take years. Therefore, the availability of effective antiviral drugs against SARS-CoV may be crucial for the control of future SARS outbreaks. In this review, experimental and clinical data about potential anti-SARS drugs is summarised and discussed. Animal model studies will be needed to help to determine which interventions warrant controlled clinical testing.

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