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Review
. 2005 May 7;330(7499):1076-9.
doi: 10.1136/bmj.330.7499.1076.

What can mendelian randomisation tell us about modifiable behavioural and environmental exposures?

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Review

What can mendelian randomisation tell us about modifiable behavioural and environmental exposures?

George Davey Smith et al. BMJ. .

Abstract

Using genetic variants as a proxy for modifiable environmental factors that are associated with disease can circumvent some of the problems of observational studies

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Figures

Figure 1
Figure 1
Comparison of design of mendelian randomisation studies and randomised controlled trials
Figure 2
Figure 2
Is sheep dip harmful? Turn to Mendelian randomisation Credit: HOLT STUDIOS/NIGEL CATLIN

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