[Results of an open prospective controlled randomized comparative trial of flurbiprofen and paracetamol efficacy and tolerance in patients with throat pain]

Abstract

Aim: To compare efficacy and safety of strepfen (flurbiprofen) to those of oral paracetamol in acute infections of the upper respiratory tracts for relief of throat pain (TP).

Material and methods: Of 60 patients 30 ones took strepfen, 30 controls took paracetamol. The intensity and dynamics of throat pain and pharyngeal discomfort were assessed by 10-point subjective visual-analog scale.

Results: Strepfen is similar by an analgetic effect to paracetamol. Strepfen acts rapidly (in 5-15 min) and its analgetic effect lasts about 3 hours. Paracetamol begins to relieve pain 30-45 min after its intake. The drug is well tolerated, serious side effects are absent.

Conclusion: Strepfen can be recommended for relief of throat pains and pharyngeal paresthesia in patients with acute and chronic pharyngeal pathology.