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Comment
. 2005 May 17;102(20):7053-4.
doi: 10.1073/pnas.0502819102. Epub 2005 May 10.

Evidence for an inflammatory process in age-related macular degeneration gains new support

Dean Bok  1
Affiliations
Comment

Evidence for an inflammatory process in age-related macular degeneration gains new support

Dean Bok. Proc Natl Acad Sci U S A. .
No abstract available

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Figures

Fig. 1.
Fig. 1.
Immunocytochemistry of a druse (D) from the eye of an 85-year-old donor. The entire druse is stained with antibodies against complement factor H (green). In the center of the druse, factor H colocalizes with the C5b-9 membrane attack complex of complement (orange). The RPE, which is distorted by the druse, contains autofluorescent lipofuscin granules (blue). Factor H staining is also visible in the lumen (L) of the capillaries, which are separated from the RPE by Brüch's membrane (BM). Colocalization of factor H and C5b-9 is also observed in the capillary wall (orange). Image is courtesy of Patrick Johnson and Kellen Betts (University of California, Santa Barbara).
See this image and copyright information in PMC

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