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Review
. 2005 Jun:20:194-200.
doi: 10.1152/physiol.00009.2005.

Physiological mechanisms of tumor-cell invasion and migration

David H Geho  1 , Russell W Bandle, Timothy Clair, Lance A Liotta
Affiliations
Free article
Review

Physiological mechanisms of tumor-cell invasion and migration

David H Geho et al. Physiology (Bethesda). 2005 Jun.
Free article

Abstract

Recent advances in understanding the complex biology of the microenvironment that underlies tumor invasion and migration have revealed novel and promising therapeutic targets. Pharmacological blockade of intra- and extracellular signaling events that regulate migration and survival of multiple cell types may disrupt the host-tumor conspiracy that allows escape from normal developmental regulation.

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