Abdominal CT findings may suggest coeliac disease
- PMID: 15893278
- DOI: 10.1016/j.dld.2004.10.016
Abdominal CT findings may suggest coeliac disease
Abstract
Background: Coeliac disease is the most common gastrointestinal immunological disorder in the western countries. Many adult patients present non-specific symptoms and signs of malabsorption such as chronic diarrhoea, anaemia, weight loss and abdominal distention. In non-specific and doubtful conditions, computed tomography is often the first medical examination performed. In a clinical practice, a critical review of computed tomography signs is therefore mandatory.
Aims: To evaluate the abdominal computed tomography findings, which are useful to suggest the presence of coeliac disease in adult patients.
Patients and methods: The computed tomography studies of 28 coeliac patients were reviewed, looking for any intestinal and extraintestinal abnormality. The computed tomography findings evaluated were: abnormalities of intestinal fold pattern, bowel dilatation, fluid and air excess, duodenal abnormalities, intestinal intussusception, bowel wall thickening, lymphadenopathy, ascites, intestinal stenosis, mesenteric vascular changes. The abdominal computed tomography of a group of 30 normal subjects was also analysed.
Results: Intestinal fold pattern abnormalities were seen in 23/28 patients. Intestinal dilatation was seen in 21/28. Fluid excess in 18/28 and lymphadenopathy was seen in 12/28 patients; engorgement of mesenteric vessels in 7/28. Bowel wall thickening was observed in 6/28 patients and transient intussusception was observed in 6/28 patients. Increased air content within the bowel in 4/28 and ascites in 2/28 patients. Bowel dilatation together with fluid excess was observed in 18/28 patients. None of the above mentioned abnormalities abnormalities were seen in normal subjects.
Conclusions: Data of the present study show that several abdominal computed tomography findings may be seen in coeliac adult patients; these findings should be taken into consideration with a high in level of suspicion by radiologists, to avoid diagnostic delay and unnecessary diagnostic and therapeutic procedures.
Comment in
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The role of CT in coeliac disease. Methodology of the studies assessing diagnostic accuracy.Dig Liver Dis. 2005 Jun;37(6):389-90. doi: 10.1016/j.dld.2005.02.001. Epub 2005 Mar 2. Dig Liver Dis. 2005. PMID: 15893275 No abstract available.
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