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. 2005 May 25;127(20):7308-9.
doi: 10.1021/ja051181d.

Pd(II)-catalyzed intermolecular 1,2-diamination of conjugated dienes

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Pd(II)-catalyzed intermolecular 1,2-diamination of conjugated dienes

Grégory L J Bar et al. J Am Chem Soc. .

Abstract

A Pd(II) chloride precatalyst, in the presence of 1 equiv of benzoquinone, effects highly efficient, regioselective 1,2-diamination of 1,3-dienes using dialkyl ureas under mild conditions. There is no requirement for a large excess of diene.

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