Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Review
. 2005 Jun 15;57(8):1109-43.
doi: 10.1016/j.addr.2005.01.020.

Near-infrared spectroscopy and imaging: basic principles and pharmaceutical applications

Gabriele Reich  1
Affiliations
Review

Near-infrared spectroscopy and imaging: basic principles and pharmaceutical applications

Gabriele Reich. Adv Drug Deliv Rev. .

Abstract

Near-infrared (NIR) spectroscopy and imaging are fast and nondestructive analytical techniques that provide chemical and physical information of virtually any matrix. In combination with multivariate data analysis these two methods open many interesting perspectives for both qualitative and quantitative analysis. This review focuses on recent pharmaceutical NIR applications and covers (1) basic principles of NIR techniques including chemometric data processing, (2) regulatory issues, (3) raw material identification and qualification, (4) direct analysis of intact solid dosage forms, and (5) process monitoring and process control.

PubMed Disclaimer

MeSH terms

Substances

LinkOut - more resources