Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Clinical Trial
. 2005 May-Jun;29(3):240-9.
doi: 10.5993/ajhb.29.3.5.

Bupropion SR vs placebo for smoking cessation in health care professionals

Jean-Pierre Zellweger  1 , Pal Laszio Boelcskei, Laura Carrozzi, Ruth Sepper, Ruth Sweet, Amy Z Hider
Affiliations
Clinical Trial

Bupropion SR vs placebo for smoking cessation in health care professionals

Jean-Pierre Zellweger et al. Am J Health Behav. 2005 May-Jun.

Abstract

Objective: To evaluate bupropion SR for smoking cessation in physicians and nurses.

Methods: This double-blind prospective 26-center, 12-country trial randomized 687 subjects to smoking cessation counselling with bupropion SR or placebo for 7 weeks. The participants were followed for 52 weeks.

Results: Bupropion SR was superior to placebo (50% vs 40%, P=0.013) on the 4-week primary outcome variable. Due to a high placebo response in this health care population, statistical differences were not maintained after treatment was discontinued.

Conclusions: Bupropion SR is effective and well tolerated in health care professionals. Relapse prevention measures are needed to attain long-term abstinence.

PubMed Disclaimer

MeSH terms

LinkOut - more resources