Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2005 May 28:(20):2589-90.
doi: 10.1039/b501939g. Epub 2005 Apr 12.

Aryl-aryl coupling via directed lithiation and oxidation

David S Surry  1 , David J Fox, Simon J F Macdonald, David R Spring
Affiliations

Aryl-aryl coupling via directed lithiation and oxidation

David S Surry et al. Chem Commun (Camb). .

Abstract

Aryl lithium reagents formed by directed lithiation reactions undergo transmetallation with copper(I) salts to form organocuprates, which may be efficiently oxidized to yield ortho-substituted biaryls.

PubMed Disclaimer

Publication types

MeSH terms

LinkOut - more resources