doi: 10.1016/s0006-291x(05)80008-7.
Melanins production from enkephalins by tyrosinase
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- PMID: 1590783
- DOI: 10.1016/s0006-291x(05)80008-7
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Melanins production from enkephalins by tyrosinase
Biochem Biophys Res Commun.
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Abstract
Leu-enkephalin and Met-enkephalin are oxidized in vitro by mushroom and sepia tyrosinase giving rise to synthetic melanins whose production is dependent on incubation time and on enzyme concentration. The Enk-melanins formed are acid-insoluble brownish or reddish pigments showing a continuous absorbance in the visible region when dissolved in basic solution. The presence of the amino acid chain makes them fully soluble in pH 7.4 0.05 M phosphate buffer and methanol.
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