Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Review
. 2005 May;2(5):e142.
doi: 10.1371/journal.pmed.0020142. Epub 2005 May 31.

The development of vaginal microbicides for the prevention of HIV transmission

Jonathan Weber  1 , Kamal Desai, Janet Darbyshire; Microbicides Development Programme
Affiliations
Review

The development of vaginal microbicides for the prevention of HIV transmission

Jonathan Weber et al. PLoS Med. 2005 May.

Abstract

Given that we still do not have an effective vaccine against HIV, the development of novel biomedical methods for preventing HIV transmission remains a top priority in controlling the HIV pandemic.

PubMed Disclaimer

Conflict of interest statement

Competing Interests: JW and JD are principal investigators on the Microbicides Development Programme, which is trialling PRO 2000.

Figures

None
Women at a Microbicides Development Programme phase III trial site
(Photo: Frank Herholdt; Copyright: © 2005 Microbicides Development Programme. This is an open-access photo distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.)
Figure 1
Figure 1. Sites of Action of Candidate Microbicides
(Illustration: Giovanni Maki)
See this image and copyright information in PMC

Similar articles

See all similar articles

Cited by

See all "Cited by" articles

References

    1. Coordinating Committee of the Global HIV/ AIDS Vaccine Enterprise. The Global HIV/AIDS Vaccine Enterprise: Scientific strategic plan. PLoS Med. 2005;2:e25. - PMC - PubMed
    1. Horton R. AIDS: The elusive vaccine. New York Rev Books. 2003 September 23;51(14):53–58.
    1. Weller S, Davis K. Condom effectiveness in reducing heterosexual HIV transmission. Cochrane Database Syst Rev. 2002;2002:CD003255. - PubMed
    1. Hicks DR, Martin LS, Getchell JP, Heath JL, Francis DP, et al. Inactivation of HTLV-III/LAV-infected cultures of normal human lymphocytes by nonoxynol-9 in vitro. Lancet. 1985;2:1422–1423. - PubMed
    1. Miller CJ, Alexander NJ, Gettie A, Hendrickx AG, Marx PA. The effect of contraceptives containing nonoxynol-9 on the genital transmission of simian immunodeficiency virus in rhesus macaques. Fertil Steril. 1992;57:1126–1128. - PubMed

MeSH terms