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Multicenter Study
. 2005 Jun;58(6):617-20.
doi: 10.1136/jcp.2004.024380.

A population based seroepidemiological survey of Chlamydia pneumoniae infections in schoolchildren

G Dal Molin  1 , B Longo, T Not, A Poli, C Campello
Affiliations
Multicenter Study

A population based seroepidemiological survey of Chlamydia pneumoniae infections in schoolchildren

G Dal Molin et al. J Clin Pathol. 2005 Jun.

Abstract

Aim: A serosurvey was carried out in schoolchildren from a northeastern area of Italy to define the burden of Chlamydia pneumoniae infection.

Methods: A sample of 649 schoolchildren underwent a simplified version of the International Study of Asthma and Allergies in Childhood questionnaire and IgG and IgA antibodies were investigated using an enzyme immunoassay, followed by a microimmunofluorescence assay in reactive sera.

Results: Of the children examined, 29% and 19.7% had IgG and IgA antibodies, respectively. The IgG prevalence increased with age. No other sociodemographical variable was related to C pneumoniae infection. An association was established between IgA prevalence and previous otitis media.

Conclusions: A mesoendemic (intermediate between high and low endemic level) pattern of C pneumoniae infection is present in schoolchildren from this area and the prevalence rate is related to age. Moreover, this is the first epidemiological evidence of the role of C pneumoniae in otitis.

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