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Review
. 2005 Jun 2;46(5):696-8.
doi: 10.1016/j.neuron.2005.05.016.

Hypocretins: waking, arousal, or action?

Craig W Berridge  1 , Rodrigo A España
Affiliations
Free article
Review

Hypocretins: waking, arousal, or action?

Craig W Berridge et al. Neuron. .
Free article

Abstract

The role of hypocretin (orexin) neurotransmission in waking and arousal, though of intense interest, is poorly understood. In this issue of Neuron, demonstrate that, in general, hypocretin neurons are minimally active during both sleep and quiet waking. In contrast, these neurons display robust activity during periods of alert and/or active waking.

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