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. 2005 Jun 10;70(12):4873-5.
doi: 10.1021/jo050036f.

Improved solution- and solid-phase preparation of hydroxamic acids from esters

Chih Y Ho  1 , Eric Strobel, Janet Ralbovsky, Robert A Galemmo Jr
Affiliations

Improved solution- and solid-phase preparation of hydroxamic acids from esters

Chih Y Ho et al. J Org Chem. .

Abstract

The addition of small amounts of solid KCN to solution and solid-phase esters in THF/MeOH/50% aqueous NH2OH increases the efficiency of their transformation to the corresponding hydroxamic acids.

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