Cancer immunotherapy based on the killing of Salmonella typhimurium-infected tumour cells
- PMID: 15934824
- DOI: 10.1517/14712598.5.4.443
Cancer immunotherapy based on the killing of Salmonella typhimurium-infected tumour cells
Abstract
The use of bacteria for anticancer purposes was first attempted over 100 years ago. Recently, several strains of Salmonella have been shown to possess anticancer activity and, interestingly, Salmonella possesses a unique propensity to track to tumour tissue in vivo. This review presents the use of Salmonella for cancer immunotherapy, including the distinguishing characteristics of this organism and preclinical as well as clinical data.
Similar articles
-
Targeted cancer immunotherapy with genetically engineered oncolytic Salmonella typhimurium.Cancer Lett. 2020 Jan 28;469:102-110. doi: 10.1016/j.canlet.2019.10.033. Epub 2019 Oct 24. Cancer Lett. 2020. PMID: 31666180 Review.
-
Optimizing Salmonella enterica serovar Typhimurium for bacteria-mediated tumor therapy.Gut Microbes. 2016;7(2):171-7. doi: 10.1080/19490976.2016.1155021. Gut Microbes. 2016. PMID: 26939530 Free PMC article. Review.
-
Cancer immunotherapy based on killing of Salmonella-infected tumor cells.Cancer Res. 2005 May 1;65(9):3920-7. doi: 10.1158/0008-5472.CAN-04-3002. Cancer Res. 2005. PMID: 15867392
-
The Boosting Potential of Bacteria in Cancer Immunotherapy.Trends Mol Med. 2017 Jul;23(7):580-582. doi: 10.1016/j.molmed.2017.05.008. Epub 2017 Jun 2. Trends Mol Med. 2017. PMID: 28583420 Free PMC article.
-
Synergistic antitumoral effects of human telomerase reverse transcriptase-mediated dual-apoptosis-related gene vector delivered by orally attenuated Salmonella enterica Serovar Typhimurium in murine tumor models.J Gene Med. 2008 Jun;10(6):690-701. doi: 10.1002/jgm.1191. J Gene Med. 2008. PMID: 18338832
Cited by
-
Progress in Adaptive Immunotherapy for Cancer in Companion Animals: Success on the Path to a Cure.Vet Sci. 2015 Dec;2(4):363-387. doi: 10.3390/vetsci2040363. Epub 2015 Oct 19. Vet Sci. 2015. PMID: 27066495 Free PMC article.
-
Tumor-targeting bacterial therapy: A potential treatment for oral cancer (Review).Oncol Lett. 2014 Dec;8(6):2359-2366. doi: 10.3892/ol.2014.2525. Epub 2014 Sep 11. Oncol Lett. 2014. PMID: 25364397 Free PMC article.
-
EGFR-targeted Chimeras of Pseudomonas ToxA released into the extracellular milieu by attenuated Salmonella selectively kill tumor cells.Biotechnol Bioeng. 2016 Dec;113(12):2698-2711. doi: 10.1002/bit.26026. Epub 2016 Jul 8. Biotechnol Bioeng. 2016. PMID: 27260220 Free PMC article.
-
Safety and immunogenicity of Salmonella typhimurium expressing C-terminal truncated human IL-2 in a murine model.Biologics. 2010 Mar 24;4:61-73. doi: 10.2147/btt.s9121. Biologics. 2010. PMID: 20376175 Free PMC article.
-
Turning the corner on therapeutic cancer vaccines.NPJ Vaccines. 2019 Feb 8;4:7. doi: 10.1038/s41541-019-0103-y. eCollection 2019. NPJ Vaccines. 2019. PMID: 30774998 Free PMC article. Review.
Publication types
MeSH terms
LinkOut - more resources
Full Text Sources
Other Literature Sources