Coordinate gene regulation by two different catenins
- PMID: 15935766
- DOI: 10.1016/j.devcel.2005.05.003
Coordinate gene regulation by two different catenins
Abstract
In this issue of Developmental Cell, McCrea and colleagues report that p120-catenin regulates the same Wnt target genes as beta-catenin in the Xenopus embryo (). These findings raise the exciting possibility that these two related proteins function in parallel to mediate cadherin-associated regulation of gene expression.
Comment on
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Kaiso/p120-catenin and TCF/beta-catenin complexes coordinately regulate canonical Wnt gene targets.Dev Cell. 2005 Jun;8(6):843-54. doi: 10.1016/j.devcel.2005.04.010. Dev Cell. 2005. PMID: 15935774
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