Standards for selected anthropometric measurements in males with the fragile X syndrome

Abstract

Standards (95th, 50th, and 5th percentiles) in fragile X syndrome for weight, height, head circumference, ear length, and testicular volume are reported. For comparison with fragile X syndrome standardized curves, normal control data from the literature were similarly plotted and curves produced. These standards reflect the physical parameters that are frequently abnormal in males with the fragile X syndrome and should be useful in the medical management of patients with this syndrome. The standards may also be used to help identify those individuals, particularly the younger males, for chromosome studies to confirm the clinical impression of the fragile X syndrome.

Fig 1

Standardized curves for weight of males with fragile X syndrome (solid line) and normal individuals (broken line).

Fig 2

Standardized curves for height of males with fragile X syndrome (solid line) and normal individuals (broken line).

Fig 3

Standardized curves for head circumference of males with fragile X syndrome (solid line) and normal individuals (broken line).

Fig 4

Standardized curves for ear length of males with fragile X syndrome (solid line) and normal individuals (broken line).

Fig 5

Standardized curves for testicular volume of males with fragile X syndrome (solid line) and normal individuals (broken line).