Review
doi: 10.1016/j.febslet.2005.04.005.
Epub 2005 Apr 18.
Linear motifs: evolutionary interaction switches
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- PMID: 15943979
- DOI: 10.1016/j.febslet.2005.04.005
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Review
Linear motifs: evolutionary interaction switches
FEBS Lett.
.
Free article
Abstract
Linear motifs are short sequence patterns associated with a particular function. They differ fundamentally from longer, globular protein domains in terms of their binding affinities, evolution and in how they are found experimentally or computationally. In this Minireview, we discuss various aspects of these critically important functional regions.
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