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Clinical Trial
. 2006 Feb;14(2):167-71.
doi: 10.1007/s00520-005-0845-0. Epub 2005 Jun 10.

Non-invasive ventilation for cancer patients with life-support techniques limitation

Anne-Pascale Meert  1 , Thierry Berghmans, Michel Hardy, Eveline Markiewicz, Jean-Paul Sculier
Affiliations
Clinical Trial

Non-invasive ventilation for cancer patients with life-support techniques limitation

Anne-Pascale Meert et al. Support Care Cancer. 2006 Feb.

Abstract

Goals of work: The study was conducted to determine the usefulness and efficacy of non-invasive ventilation (NIV) in cancer patients with "life-support techniques limitation" admitted for an acute respiratory distress, in terms of intensive care unit (ICU) and hospital discharges.

Patients and methods: A total of 18 consecutive cancer patients (17 with solid tumours and one with haematological malignancy) with "life-support techniques limitation" in acute respiratory failure and who benefited from NIV were included. NIV was provided with a standard face mask by the BiPAP Vision ventilator (Respironics Inc.). Variables related to the demographic parameters, SAPS II score, cancer characteristics, intensive care data and hospital discharge were recorded.

Main results: Complications leading to NIV were hypoxemic respiratory failure in 11 patients and hypercapnic respiratory failure in seven. Total median duration of NIV was 29 h. NIV was applied during a median of 2.5 days with a median of 16 h per day. Total median ICU stay was 7 days (range 1-21). Fourteen and ten patients were discharged from ICU and from hospital, respectively.

Conclusion: NIV appears to be an effective ventilation support for cancer patients with "life-support techniques limitation".

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