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Review
. 2005 Sep-Oct;87(9-10):805-11.
doi: 10.1016/j.biochi.2005.04.014.

Translational control during mitosis

Magali Le Breton  1 , Patrick Cormier, Robert Bellé, Odile Mulner-Lorillon, Julia Morales
Affiliations
Review

Translational control during mitosis

Magali Le Breton et al. Biochimie. 2005 Sep-Oct.

Abstract

Translation is now recognized as an important process in the regulation of gene expression. During the cell cycle, translation is tightly regulated. Protein synthesis is necessary for entry into and progression through mitosis and conversely, modifications of translational activity are observed during the cell cycle. This review focuses on translational control during mitosis (or M-phase) and the role of CDK1/cyclin B, the universal cell cycle regulator implicated in the G2/M transition, in protein synthesis regulation.

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