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Review
. 1992 May;17(5):187-91.
doi: 10.1016/0968-0004(92)90264-a.

Chromatin dynamics and the modulation of genetic activity

J C Hansen  1 , J Ausio
Affiliations
Review

Chromatin dynamics and the modulation of genetic activity

J C Hansen et al. Trends Biochem Sci. 1992 May.

Abstract

Chromatin, the genetic material of eukaryotes, is a dynamic macromolecular assembly that continuously changes its composition and conformation to accommodate different stages of genetic activity, e.g. transcription and replication. Evidence is accumulating that the dynamic behavior of chromatin has important functional roles in the modulation of genetic activity, largely due to the intrinsic properties of arrays of nucleosome cores.

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