Chronic recurrent varicella-zoster virus keratitis confirmed by polymerase chain reaction testing
- PMID: 15953460
- DOI: 10.1016/j.ajo.2004.12.014
Chronic recurrent varicella-zoster virus keratitis confirmed by polymerase chain reaction testing
Abstract
Purpose: To report a case of chronic recurrent varicella virus epithelial keratitis in a child.
Design: Case report.
Methods: Clinical examination and polymerase chain reaction analysis of corneal epithelium.
Results: A 10-year-old healthy child developed chronic recurrent varicella virus keratitis with pseudodendrites after recovering from systemic varicella. Analysis of the debrided pseudodendrites was repeatedly positive for VZV DNA and negative for HSV DNA. Treatment with oral acyclovir and topical corticosteroid drops was effective in eliminating the pseudodendrites; however, recurrences occurred once the medications were discontinued.
Conclusions: Varicella virus epithelial keratitis in children can be a recurrent chronic condition requiring prolonged treatment.
Comment in
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Chronic recurrent varicella-zoster virus keratitis confirmed by polymerase chain reaction testing.Am J Ophthalmol. 2006 Apr;141(4):782; author reply 782. doi: 10.1016/j.ajo.2005.12.023. Am J Ophthalmol. 2006. PMID: 16564841 No abstract available.
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