Review
[Molecular-genetic approaches to diagnosis and intraspecific typing of causative agents of glanders and melioidosis]
[Article in
Russian]
- PMID: 15954468
Item in Clipboard
Review
[Molecular-genetic approaches to diagnosis and intraspecific typing of causative agents of glanders and melioidosis]
[Article in
Russian]
Mol Gen Mikrobiol Virusol.
2005.
Abstract
Pathogenic Burkholderia--Burkholderia mallei and Burkholderia pseudomallei--are causative agents of glanders and melioidosis, severe infectious diseases of man and animals. They are regarded as potential agents of bioterrorism. The existing bacteriological and immunological methods of identification of B. mallei and B. pseudomallei are not efficient enough for the rapid diagnosis and typing of strains. Described in the paper are molecular methods of detection of the agents by PCR, hybridization and strain typing made on the basis of bacterial total cell protein profiles, RAPD, ribotyping as well as of plasmid and DNA microrestriction analyses.
Similar articles
-
Molecular identification and typing of Burkholderia pseudomallei and Burkholderia mallei: when is enough enough?Trans R Soc Trop Med Hyg. 2008 Dec;102 Suppl 1:S134-9. doi: 10.1016/S0035-9203(08)70030-0. Trans R Soc Trop Med Hyg. 2008. PMID: 19121675
-
[Identification of the causative agents of glanders and melioidosis by polymerase chain reaction].Mol Gen Mikrobiol Virusol. 2003;(3):18-22. Mol Gen Mikrobiol Virusol. 2003. PMID: 12966921 Russian.
-
Development of a polymerase chain reaction assay for the specific identification of Burkholderia mallei and differentiation from Burkholderia pseudomallei and other closely related Burkholderiaceae.Diagn Microbiol Infect Dis. 2006 May;55(1):37-45. doi: 10.1016/j.diagmicrobio.2005.11.007. Epub 2006 Mar 20. Diagn Microbiol Infect Dis. 2006. PMID: 16546342
-
Burkholderia mallei and Burkholderia pseudomallei: the causative micro-organisms of glanders and melioidosis.Recent Pat Antiinfect Drug Discov. 2007 Nov;2(3):233-41. doi: 10.2174/157489107782497335. Recent Pat Antiinfect Drug Discov. 2007. PMID: 18221181 Review.
-
Molecular insights into Burkholderia pseudomallei and Burkholderia mallei pathogenesis.Annu Rev Microbiol. 2010;64:495-517. doi: 10.1146/annurev.micro.112408.134030. Annu Rev Microbiol. 2010. PMID: 20528691 Review.