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. 2005 Jun 23;7(13):2771-4.
doi: 10.1021/ol050970x.

Alpha-hydroxy cyclopentenones from alpha-diketones

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Alpha-hydroxy cyclopentenones from alpha-diketones

William A Batson et al. Org Lett. .

Abstract

[reaction: see text] Metalloenolates derived from alpha,beta-unsaturated alpha-diketones undergo cyclization to alpha-hydroxy cyclopentenones. This is apparently the first reported Nazarov reaction that takes place in the presence of base.

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