Review
doi: 10.1016/j.cell.2005.06.001.
Getting downstream without a Raft
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- PMID: 15960968
- DOI: 10.1016/j.cell.2005.06.001
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Review
Getting downstream without a Raft
Cell.
.
Free article
Abstract
The role of plasma-membrane microdomains in the organization of signaling proteins has been a controversial topic in T cell signaling. In this issue of Cell, use of single-molecule fluorescence suggests that protein-protein interactions, not detergent insolubility, regulate the assembly of signaling complexes in the plasma membrane.
Comment on
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Single-molecule microscopy reveals plasma membrane microdomains created by protein-protein networks that exclude or trap signaling molecules in T cells.Cell. 2005 Jun 17;121(6):937-50. doi: 10.1016/j.cell.2005.04.009. Cell. 2005. PMID: 15960980 Free PMC article.
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