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Case Reports
. 2005 Jul-Aug;14(4):281-3.
doi: 10.1159/000085751.

Late development of diabetes mellitus after interferon-alfa and ribavirin therapy for chronic hepatitis C: a case report

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Free article
Case Reports

Late development of diabetes mellitus after interferon-alfa and ribavirin therapy for chronic hepatitis C: a case report

Sivasankara Radhakrishnan et al. Med Princ Pract. 2005 Jul-Aug.
Free article

Abstract

Objective: To report the late development of immune-mediated diabetes mellitus after completion of alfa-interferon therapy for hepatitis C in an Asian patient.

Clinical presentation and intervention: A 50-year-old male with chronic hepatitis C received treatment with alfa-interferon and ribavirin for 52 weeks. He developed immune-mediated diabetes mellitus with low C-peptide and positive antiglutamic acid decarboxylase antibody after completion of therapy. The hepatitis C infection was eradicated, but he continued to be diabetic requiring insulin therapy during the follow-up.

Conclusion: This report shows thatimmune-mediateddiabetes mellitus can occur as a late complication of alfa-interferon therapy.

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