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Review
. 2005 May:Suppl:S8-9.
doi: 10.1038/nrd1727.

Bevacizumab

Lee M Ellis  1
Affiliations
Review

Bevacizumab

Lee M Ellis. Nat Rev Drug Discov. 2005 May.

Abstract

Bevacizumab (Avastin; Genentech/Roche), an antibody against vascular endothelial growth factor, was approved by the US FDA in February 2004 for the first-line treatment of metastatic colorectal cancer in combination with 5-fluorouracil-based chemotherapy. It is the first approved agent to target tumour angiogenesis.

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