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. 2005 Jun;11(6):977-9.
doi: 10.3201/eid1106.050143.

Rifampin-resistant meningococcal disease

Jean Rainbow  1 , Elizabeth Cebelinski, Joanne Bartkus, Anita Glennen, Dave Boxrud, Ruth Lynfield
Affiliations

Rifampin-resistant meningococcal disease

Jean Rainbow et al. Emerg Infect Dis. 2005 Jun.

Abstract

Rifampin-resistant meningococcal disease occurred in a child who had completed rifampin chemoprophylaxis for exposure to a sibling with meningococcemia. Susceptibility testing of 331 case isolates found only 1 other case of rifampin-resistant disease in Minnesota, USA, during 11 years of statewide surveillance. Point mutations in the RNA polymerase Beta subunit (rpoB) gene were found in isolates from each rifampin-resistant case-patient.

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