Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 1992 May;50(5):404-10.
doi: 10.1007/BF00296770.

Bone mass and bone cellular variations after five months of physical training in rhesus monkeys: histomorphometric study

Affiliations

Bone mass and bone cellular variations after five months of physical training in rhesus monkeys: histomorphometric study

S Bourrin et al. Calcif Tissue Int. 1992 May.

Abstract

Five Rhesus Monkeys (Macaca mulatta), a suitable nonhuman model, performed 5 months of rope-climbing exercise. Duration of the training sessions was progressively increased to reach 1 hour/day after 1 month of training and was maintained until the end of the experiment. Bone mass parameters, bone resorption, and bone formation activity were measured by histomorphometric analysis on iliac crest bone biopsies before and after the experiment. Mineral apposition rate was measured in cortices and trabecular bone after double calcein labeling. Five months of rope-climbing exercise had determined a significant decrease of bone volume with a slight decrease of the number and thickness of trabeculae. This might induce an alteration of biomechanical properties of bone. These architectural modifications were associated with a nonsignificant decrease of bone resorption activity. But the main effect of training was an important decrease of bone formation activity without change of the mineral apposition rate. Endurance exercise at low intensity has determined a decreased bone turnover with osteoblastic depression. This animal experiment points out that exercise modalities might be important in the bone response to training and should be carefully defined for preventive use in humans.

PubMed Disclaimer

Similar articles

Cited by

References

    1. Med Sci Sports Exerc. 1990 Jun;22(3):281-5 - PubMed
    1. J Appl Physiol Respir Environ Exerc Physiol. 1983 Oct;55(4):1173-7 - PubMed
    1. Bone. 1989;10 (5):341-4 - PubMed
    1. J Med Primatol. 1990;19(6):583-94 - PubMed
    1. Am J Anat. 1970 Dec;129(4):477-9 - PubMed

LinkOut - more resources