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Case Reports
. 2005 Jun 18;37(3):331.

[Neurolymphomatosis, a case report]

[Article in Chinese]
Affiliations
  • PMID: 15968331
Free article
Case Reports

[Neurolymphomatosis, a case report]

[Article in Chinese]
Hong-yan Bi et al. Beijing Da Xue Xue Bao Yi Xue Ban. .
Free article

Abstract

Neurolymphomatosis (NL) is characterized by lymphomatous infiltration of the peripheral nervous system. We report a case of neurolymphomatosis (NL) which was confirmed by sural nerve biopsy. Sural nerve specimen from a 49-year-old female patient with weakness of limbs was examined with routine histochemical and immunohistochemistry staining, in which the first antibodies against CD3, CD20, CD45, CD45RO and CD68 were used. Numerous T-lymphoma cells invaded in the adipose tissue of epineurium of sural nerve. The nerve biopsy showed marked axonal degeneration of myelinated fibers. The clinical and histopathologic findings confirmed the diagnosis of neurolymphomatosis.

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