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Meta-Analysis
. 2005 Jun;2(6):e168; quiz e217.
doi: 10.1371/journal.pmed.0020168. Epub 2005 Jun 28.

Vitamin C for preventing and treating the common cold

Affiliations
Meta-Analysis

Vitamin C for preventing and treating the common cold

Robert M Douglas et al. PLoS Med. 2005 Jun.

Abstract

Whether vitamin C has an effect on the common cold has been a subject of controversy for at least 60 years. What does the evidence show?

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Conflict of interest statement

Competing Interests: RMD was an organising author of one of the papers considered in the review. HH declares that he has no competing interests.

Figures

Figure 1
Figure 1. 500-mg Vitamin C Tablets and Paprikas
Vitamin C was identified in the 1930s by Albert Szent-Györgyi, who received his Nobel Prize partly for this work. He found that paprika is a particularly rich source of the vitamin, which made it possible to produce kilograms of it for research purposes ([1963] Annu Rev Biochem 32: 1–14). Nowadays, the most convenient way to increase vitamin C intake is by way of 500-mg tablets, but further research is needed to explore the conditions in which supplementation may be beneficial.

Comment in

  • Misleading information on the properties of vitamin C.
    Hickey S, Roberts H. Hickey S, et al. PLoS Med. 2005 Sep;2(9):e307; author reply e309. doi: 10.1371/journal.pmed.0020307. Epub 2005 Sep 27. PLoS Med. 2005. PMID: 16173838 Free PMC article. No abstract available.
  • Narrow scope of vitamin C review.
    Sardi W. Sardi W. PLoS Med. 2005 Sep;2(9):e308; author reply e309. doi: 10.1371/journal.pmed.0020308. Epub 2005 Sep 27. PLoS Med. 2005. PMID: 16173839 Free PMC article. No abstract available.

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References

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