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Comparative Study
. 1979 Nov-Dec;24(6):1048-53.

[Quantitative model of human erythrocyte glycolysis. Region of cell viability determined by ATP concentration]

[Article in Russian]
F I Ataullakhanov, V M Vitvitskiĭ, A M Zhabotinskiĭ, A V Pichugin, B N Kholodenko
  • PMID: 159725
Comparative Study

[Quantitative model of human erythrocyte glycolysis. Region of cell viability determined by ATP concentration]

[Article in Russian]
F I Ataullakhanov et al. Biofizika. 1979 Nov-Dec.

Abstract

The boundaries of the cell vitality domain in the enzyme activity space are calculated on the basis of a mathematical model of erythrocyte glycolysis. The boundaries are determined by key metabolite concentrations. The results obtained are compared with experimental data related to erythrocytic enzymopathies. It is shown that theoretical boundary enzyme activities coincide with the activities of hexokinase and in some cases phosphofruktokinase in enzyme deficient erythrocytes.

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