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Comparative Study
. 2005 Jul;32(7):458-63.
doi: 10.1097/01.olq.0000168280.34424.58.

Risk factors for early syphilis among gay and bisexual men seen in an STD clinic: San Francisco, 2002-2003

William Wong  1 , Janice K Chaw, Charlotte K Kent, Jeffrey D Klausner
Affiliations
Comparative Study

Risk factors for early syphilis among gay and bisexual men seen in an STD clinic: San Francisco, 2002-2003

William Wong et al. Sex Transm Dis. 2005 Jul.

Abstract

Background: Substantial increases in syphilis among gay and bisexual men have been reported in San Francisco.

Goal: To identify risk factors for early syphilis infection among gay and bisexual men attending the San Francisco municipal STD clinic (City Clinic).

Study: Cross-sectional, self-administered, behavioral survey of gay and bisexual men attending City Clinic between November 2002 and March 2003 linked with electronic medical record data.

Results: Among 1318 gay and bisexual men surveyed, 53 (4.0%) were diagnosed with early syphilis. The final multivariate model included nonwhite race (OR = 2.1 [1.1-4.4]), HIV-infection (OR = 3.9 [2.0-7.7]), using both methamphetamine and sildenafil (Viagra(R)) (OR = 6.2 [2.6-14.9]), using methamphetamine without sildenafil (OR = 3.2 [1.3-7.6]), using sildenafil without methamphetamines (OR = 0.9 [0.3-2.9]), stronger gay community affiliation (OR = 2.3 [1.2-4.6]), and having recent Internet partners (OR = 2.1 [1.0-4.3]).

Conclusions: Syphilis prevention efforts should address methamphetamine and sildenafil use among gay and bisexual men and require strong and substantive involvement with the gay community to address syphilis in San Francisco.

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