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Review
. 2005 Aug;83(8):596-600.
doi: 10.1007/s00109-005-0682-0. Epub 2005 Jun 23.

Bmi1 in development and tumorigenesis of the central nervous system

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Free article
Review

Bmi1 in development and tumorigenesis of the central nervous system

Olga Shakhova et al. J Mol Med (Berl). 2005 Aug.
Free article

Abstract

The role of the Polycomb group gene Bmi1 in proliferation control of lymphoid and neuronal progenitors as well as in self-renewal of haematopoietic and neural stem cells has been recently demonstrated. Here we review these recent findings with particular regard to their implications for central nervous system development and tumorigenesis.

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