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Review
. 2005 Jul;21(7):578-81.
doi: 10.1007/s00383-005-1451-4. Epub 2005 Jun 24.

Caudal regression syndrome--case report and review of literature

Santosh Kumar Singh  1 , Rupa Dalmia Singh, Akhilesh Sharma
Affiliations
Review

Caudal regression syndrome--case report and review of literature

Santosh Kumar Singh et al. Pediatr Surg Int. 2005 Jul.

Abstract

Caudal regression syndrome is a rare disorder of distal spinal segments affecting the development of the spinal cord, with attendant sequelae. Intelligence is preserved. The exact etiology is elusive, though maternal diabetes, genetic factors, and hypoperfusion might play roles. Recently, the role of teratogens has been studied in animal models. Treatment is difficult, multidisciplinary, and largely supportive. Lower limb deformities with sensory and motor loss and neurogenic bladder call for intensive and long-term attention.

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