Broader distribution of plasmid-mediated quinolone resistance in the United States
- PMID: 15980384
- PMCID: PMC1168650
- DOI: 10.1128/AAC.49.7.3001-3003.2005
Broader distribution of plasmid-mediated quinolone resistance in the United States
Abstract
The plasmid-encoded quinolone resistance gene qnrA confers low-level quinolone resistance, facilitating selection of higher-level resistance. Epidemiologic surveys for qnrA were extended to isolates of Enterobacter spp. and to quinolone-susceptible Enterobacteriaceae. Two (10%) of 20 ceftazidime-resistant quinolone-susceptible Klebsiella pneumoniae strains carried the gene, as did 12 (17%) of 71 ceftazidime-resistant Enterobacter strains from across the United States. One of these Enterobacter isolates was quinolone susceptible. Thus, qnrA is present in quinolone-resistant and quinolone-susceptible Enterobacter and Klebsiella strains in the United States.
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References
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- Jacob, A. E., J. A. Shapiro, L. Yamamoto, D. I. Smith, and S. N. Cohen. 1977. Plasmids studied in Escherichia coli and other enteric bacteria, p. 607-638. In A. I. Bukhari, J. A. Shapiro, and S. L. Adhya (ed.), DNA insertion elements, plasmids, and episomes. Cold Spring Harbor Laboratory, Cold Spring Harbor, N.Y.
-
- Macrina, F. L., D. J. Kopecko, K. R. Jones, D. J. Ayers, and S. M. McCowen. 1978. A multiple plasmid-containing Escherichia coli strain: convenient source of size reference plasmid molecules. Plasmid 1:417-420. - PubMed
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