The mycobacteria story in Crohn's disease
- PMID: 15984977
- DOI: 10.1111/j.1572-0241.2005.50358.x
The mycobacteria story in Crohn's disease
Abstract
The heterogeneity of Crohn's disease suggests that it would be unwise to dismiss an infectious contribution to the pathogenesis in a subset of patients. The most enduring infectious candidate has been Mycobacterium paratuberculosis, which appears to be widespread in nature and appears to have the potential to infect humans. However, there are many counterarguments to the notion that MAP causes Crohn's disease, and numerous observations are seemingly at variance with this concept.
Comment in
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Mycobacterium avium subspecies paratuberculosis: a human pathogen causing most cases of Crohn's disease.Am J Gastroenterol. 2006 May;101(5):1157-8; author reply 1158. doi: 10.1111/j.1572-0241.2006.00583_5.x. Am J Gastroenterol. 2006. PMID: 16696794 No abstract available.
Comment on
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Detection and Isolation of Mycobacterium avium subspecies paratuberculosis from intestinal mucosal biopsies of patients with and without Crohn's disease in Sardinia.Am J Gastroenterol. 2005 Jul;100(7):1529-36. doi: 10.1111/j.1572-0241.2005.41415.x. Am J Gastroenterol. 2005. PMID: 15984976
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