Anion-mediated phase transfer of Zinc(II)-coordinated tyrosine derivatives

Abstract

[reaction: see text] Tyrosine-derived Zn(2+) coordination complexes and their fluorescent NBD conjugates are synthesized in a short, high-yielding procedure. The Zn(2+) complexes are highly water soluble, but in the presence of sodium laurate they readily transfer into an octanol layer. Furthermore, the NBD-labeled bis-Zn(2+) complex can partition into vesicle membranes containing anionic phospholipids.