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Comment
. 2005 Jun;9(3):247-8.
doi: 10.1186/cc3523. Epub 2005 Apr 18.

Narcotic-based sedation regimens for critically ill mechanically ventilated patients

Pratik Pandharipande  1 , E Wesley Ely
Affiliations
Comment

Narcotic-based sedation regimens for critically ill mechanically ventilated patients

Pratik Pandharipande et al. Crit Care. 2005 Jun.

Abstract

Sedatives and analgesics are routinely used in the intensive care unit to relieve pain and anxiety. These agents have numerous side effects and may contribute to poor outcomes such as increased length of mechanical ventilation, longer ICU stays and acute and long-term cognitive dysfunction. Modifying sedation paradigms utilizing either narcotic-based regimens with remifentanil or fentanyl, or by using alpha2 agonists such as dexmedetomidine may help in improving these outcomes in critically ill patients.

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