Can mupirocin prevent methicillin-resistant Staphylococcus aureus infections?
- PMID: 15987417
- PMCID: PMC1175903
- DOI: 10.1186/cc3720
Can mupirocin prevent methicillin-resistant Staphylococcus aureus infections?
Abstract
In a retrospective study, Dr Muller and colleagues have assessed the efficacy of mupirocin nasal ointment alongside hygienic measures in methicillin-resistant Staphylococcus aureus (MRSA)-positive patients admitted to the intensive care unit (ICU). Their findings, which suggest that intranasal mupirocin can prevent ICU-related MRSA infections, need confirmation in a well-designed clinical trial. In general: early identification, isolation and treatment of all MRSA carriers, including health care workers, and disinfection of contaminated environments, are the main 'ingredients' of an effective MRSA 'search and destroy' program.
Comment on
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Use of intranasal mupirocin to prevent methicillin-resistant Staphylococcus aureus infection in intensive care units.Crit Care. 2005 Jun;9(3):R246-50. doi: 10.1186/cc3512. Epub 2005 Mar 31. Crit Care. 2005. PMID: 15987397 Free PMC article.
References
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